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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07bf1464e751af6dfe1380963c96cf19281b3bf6651bcf85ef1ccc8d51c5157b' 
  AND token = 'IQ1FvbEXzopiH8JYn17RrfggdW2QO2hYQptFmH3HiPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}