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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cffc9bad4cbf029b131ac3f138dbb1c6183afe212480209ed79b6657961d400' 
  AND token = '2xbhSEpM7lpZ+Y2x49U3taHIZD33qo+Npu5ltJN8OXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}