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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d7d97bc7c64d9dfa9646e4226dff6453766defd9ca2c9ed0b8d3978bc6621e' 
  AND token = 'pwujdcm4gtlwMgHPic7Ckw1ncyduMV1OurG3imW4Jpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}