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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c2372a039563deb1cca7b76ce3d76b36117ade6d454f2addc14e6d754e89b8' 
  AND token = '81OCmuC8HeiAX9FztIY2wwVftILCQ78OjpiV+BfmLxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}