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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8cdcff785916c6846fb8f7fd05aa726f76996ae24b004fc11d992559451d6d0' 
  AND token = 'AH2JyrU7D+uYgh/fCTVc3prAmfaZH91w0hZAMMKF5oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}