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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f114d203cfe75c25994952b1d6e08c99ec16e200ae3b4bf0141dab2e19ff63ba' 
  AND token = 'K7YaXdttBJn+XzvROKz9Kf6Vid3Lz/YaGYQ1iuT5tHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}