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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a63b2f4722b652168cb3ee275d38173d179f83bb15c40c165e46f4e51a1b79b' 
  AND token = 'V/mp1U1P1ajPpp3R/iuxoqjeJ4IGtRjSD+nrSp5V0tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}