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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a96a11bd5c6c2596a3724522b06c16d97276eb68d4ea58df5326a748e03972' 
  AND token = '53hQK4HyyOCMfQj8FKmaZyNoC0bUb8cHBI/V/ncneF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}