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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e154f3e3b82db237258c8601a477fb68d9dfb846684cc204291270fd829326a2' 
  AND token = 'ArI9ZyQX/c4qZsUy8MEL3KWLo9X55wE2QbCUghsSrDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}