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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffa7413ec1e0744c525e272eecf792fe174ff9885df78a5479c1f438d7f41fa' 
  AND token = 'SMRUTMWQc9biumAUWDCDxhsN7SnCFd5sBVM6Z+2F7Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.01017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}