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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c16c2b2eecc6ee34ad417a872822ade48a811fa273f1df406eebf1aa035fcb2' 
  AND token = 'nxna+SBk6lLLwuvJ6uQ5CtB6wF1XJ61mcYqx/DWimGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}