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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd37b0ba1142fbe3c1f589858f21454939dcb7827604942fa0db08b1cd1a4a20' 
  AND token = 'a9IHXqz1WM9aSggvHV4E/dTREp2bM+sQS/jj0Q4BiRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}