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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b7ec25795ceec2311b7beda8a0977d43ed5a965558a542a7f5167d0a21dfaf1' 
  AND token = '4Ns2AyQul1hD8TjKd9m+SUoD/3a24rSvxJEp2tSCKuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}