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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f61cecb02ca95ca954f102984e5e6e278c84d01af82dcb79f39ec76d85027139' 
  AND token = 'KAWRUExsB1l3c8uobfSBBtL1PGm5QkkxLZbuJwxkk+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}