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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af8187fe00dde21a19a893ba992961d3cb7b1bfdcae407a1c1e9047490674794' 
  AND token = 'Hfjh4lb+CHZIe87myL82iDcWn6xT19QbvdHiWGtfjyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}