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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17849a38517ed9111b232f88fb02b77bd86072b84ad923a9946bfb6e24ce37c3' 
  AND token = 'JDtf5b1faRutFHvg8UWWcC1netqgFNgL/OQ9dB/hA6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}