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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c7351ff675a63b4d747d40b909b497477378557cb8b55696d457b37be34a3e4' 
  AND token = 'dNEB6qh00JdGPLqrEnfFon5W3tlgOfYScjxDH6p7lkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}