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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e589c4ff29dcd3a8d5215f5a860aaf6bacd6dba4010199975921c76a13374b0d' 
  AND token = '6lFZG4E0YCU4ObqpwaAm/BxIfRFBJomYPed8o6S5ScE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}