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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c367e51f13ce85d8f277b9190bc8e9e9361dc6826be4295d261ddd39a59b0f2' 
  AND token = 'yFpemM0T8kf2t0X6ww7dVHGV+pGgGPtnCYwYM+4vNFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}