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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c0147db48285debc20241ae69418dcc8cbe9478d45bb3f71a9e4333505a3478' 
  AND token = 'aCq48YJZOcGs6h45gEnfeignacew3tGTgsBpbE+efbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}