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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdbde4fe06f4bd167d3da6210994224263c3c9fecc1aecd5a5bdcdd88439d28d' 
  AND token = 'vk8v/r8RhTlE5LWcBl1o13EQWGZlZOxC0WDMiyV0zS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}