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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cff6348423ea6759dda2ac5b86529bc3ba733091c3ffd0d35f15ef40ce8266f' 
  AND token = 'MW07PxMBotDNJYwzNm9/PmgLNb9pv1F6TQJ9TEceQQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}