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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee7b05e7227e7745a3506781eae5a5fd185ed105d64e70add0dbf4b43fb58a2' 
  AND token = 'W9KeBXU4y0F1iKm0Lki/F5lz8c7vq6SnX2oVIZ6hRd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}