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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2285f9fd840ace663e47a180b9adcd8406e4ca305d7c0f96a244a266e734da67' 
  AND token = 'cE4TK17kJckgUsmJ3QiGD6dq0Aq2NJMjIscE4aTE4q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}