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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09341d5976952c5d2a2cfe3695286f17e2cb6361c5cccfaea8a1de01f80eb142' 
  AND token = 'kVcjE/auCLqDTdECSB5DrbUQUZ9lTlWpG2yEIuN3U6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}