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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01555f1961a47b407ca17b41feb1993a86d4f282344d1f1e0bdbd98063be14b6' 
  AND token = 'skDRvg/urcm/xcSQ1UZW6Esx+9flBeuBfTfWyTY0Rp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}