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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b9e0d1f4b07f60d3c2efe1c7e55faeed8ec8b1a720e1845ea45b7a502351513' 
  AND token = 'k2CGgn2I2V/AH9GjvdpuILkuJlr5wd9cFG9Nonty22Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}