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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b28dfe2bdf76866dd83c49dba8cd5640d447db0dd6170e04dba908af9566fa48' 
  AND token = 'ddpGotdnpGTg2LhWeo+5Uw5DDmRYaz6+TKQdCtkxv+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}