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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778e4a5260ab6224c8c6ff85761e4576294ec9fb9a0f965d2fdf2576889e8c90' 
  AND token = 'cGGjQc2Jgro/BKg6LXD99YaV7hNjEyu7aFEPRt/tY/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}