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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f488e981afe60013f22b36112e97231deeb600cea1fbe464c91b2d4065182c' 
  AND token = '517hcs1atyZ4ShgHGDbvH4BxZbagGw6IW7Wvdt3n/Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}