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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe295e5418f6335202b70c4c6ed4ac4d08a8cab204aa160b811f8e0da76bbe9f' 
  AND token = 'rek3M7YV95CdanqVlzjrYr6V6O80mH26SerwIW1Q6nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}