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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a289675620aa8236ad1f940a62d638a78682382d7c61702ee46c9613d568a8e9' 
  AND token = '/o/Gk+37aYxulI3nyNOu5sWBlOP+nPNbgFShyYmwhE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}