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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a3b2b56c538ff70b27bdadab02b4385538cbab96f9169ec5a0c0776181e48d0' 
  AND token = '5IJxYx6M0LcEIfxDWAiasqCnKPDlL1iOUxtBUpwsmVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}