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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5b7e1df81048673d3054258ca89589207b0401bc47c195d21fd0f23be08bd5' 
  AND token = 'sw1XzOL8a4wLKrFO0VaNwFfJ7R8/HvHTYY267HVxkFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}