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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d12867eb62e3ebf2998d041faa9ed0a9069fa9b6208c2d33bf04ead10bdae0' 
  AND token = 't5q+q8rAhJENOPOcpX62YtNPT5XbiMEfxSM2utWfCYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}