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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09f4331b08d1832528951531c32ea3330ad29ba5d87c9d93a8196a5113e7a473' 
  AND token = 'vg+xqqmcSHPmqORzHTw9UINAkgSrbB6W1Mdi7Oc9NVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}