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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ed5d9eb9468ca893b1ccf31b27f59a46da4d21d4938354da9ece47844156ab' 
  AND token = 'IEY5XKJLhJdTXb7eHnhQ9yM+Z33PSAFA123MXM9b5SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}