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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a58fa5e1f0b0644266d5545d44e8bcea886d7963495e0336a56b36e9a93f6ef3' 
  AND token = 'IGLAYVG86eM6B+yQZH3GtBaL59cOin/fZa+pFxA7Ojg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}