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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e09fc60a5f2042a5cb70259145a4b27433fbf7479c5e466b5ba76ca8494c3256' 
  AND token = 'p7S6fZXRZCHJ1m9ZUTO+LjvRLQmIS/XlzbRIIiuelu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}