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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465e0e908200ee1df46828fbcc301dbc4013afdd92e0622a720990965b168949' 
  AND token = '31LOxlY22yxPi9pRfW+LgNvaIPHDjZbAAOH9BAdIloI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}