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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d97b54ac096eeeea15f18287b1c9240882af7ed41adaa591d0608114afde6e' 
  AND token = 'XZp4LWJnMmXBUU5z5uxbHWXJf/HCNnREcMzwwh2X1oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}