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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5d6a5f12672fee6e24e3fb979a920b6c3bf48da0c973d188a6be39ed2d9264' 
  AND token = '7YwfhzdXNSvI8rymdjeZtA1/G0rkNUxSIfLbE1vUYzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}