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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a82152233b434be7b7eef2a0c4d36720a3732835011ec7eea69d8fc21a4acdd' 
  AND token = '0q+sDDrrdnCrqnR8HHdF6o6qsXxmI86dyHPlopc3Ydc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}