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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f0d5615efff25dbf9dbb4ebe3679005fc80e2636720f8ca1593da24cb4f5e6' 
  AND token = '7+C8S+Ujz8+46YNNM+8y4rRXaXzogyY71xT73SBTECU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}