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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6aedb8450a0b1befc2933a5a909cf120b95b0194396eb2e6d4116f6c2891238' 
  AND token = 'SX1mOk+6pLUnVPY8PQKqau+UggM3a3s/XbjzcxbEjHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}