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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d427dabeb28402dc44ffec4fb8f6465c9f6579f22e4bea26fec6105e1a8dbd' 
  AND token = 'rrB+bWhii1qXEP+g8nI6A/8JPV9K6mJEgIK7V/uZIIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}