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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8e5b6243eae5c28ee05356e9853c4a204bc2caeb7ca3d952cd8424d2779c0f' 
  AND token = '7qNQTGIZT1mXAin/23RomIPS7dieVGWLGfTvPlFq8A8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}