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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163f4854bafc54bdb336f6dedee0dd6dae5ffafec2db7949d1b95e82cfe6c774' 
  AND token = 'BkfDHfoBNqzetDxzshuzRh5nmxFAOOlQ+j/w4FxMHu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}