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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d5da3f7c12149e3112e648eb6908f2be6db488df675f7c7b8e72f5df77685f' 
  AND token = 'u7kXCZdkeNsF8P9fhbMxSRy1XF3C0G1aoJrThm0itWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}