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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a979885c6fe42fb82a6c955d2df311863188f3963e07df49f9c2d49ea13dc28' 
  AND token = 'FU+6EnwGa4TTG1gEggP4iy9srnnwmA3rRz5UKNdp3UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}